Coding
Part:BBa_K2239012:Design
Designed by: Ruohong Wang Group: iGEM17_SDSZ-China (2017-09-29)
7beta-HSDH
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 448
- 1000COMPATIBLE WITH RFC[1000]
Source
The 7beta-HSDH DNA is originally from the genome of R. torques ATCC 35915, and is artificially synthesized based on the sequence retrieved from the GenBank.
References
[1] Ming-Min Zheng, Ru-Feng Wang, Chun-Xiu Li, Jian-He Xu: Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques. Process Biochemistry, Elsevier, 2015.